BMS-986260
Catalog No.
BA9165
BMS-986260 is an immuno-oncologically active molecule and is a potent, selective
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BMS-986260 is an immuno-oncologically active molecule and a potent, selective, orally active inhibitor (=1.6 nM).BMS-986260 is more selective for TGFβR1 than for its cognate TGFβR2 and shows this selectivity in a set of more than 200 kinases tested.BMS-986260 inhibits TGFβ in both MINK and NHLF cell lines inhibited TGFβ-mediated pSMAD2/3 nuclear translocation with ICs of 350 nM and 190 nM, respectively.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 382.78 |
| Cas No. | 2001559-19-7 |
| Formula | C18H12ClFN6O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |