Signaling pathways
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BA2738 DB2313Summary: DB2313 is a potent inhibitor of transcription factors. - BA2739 ACBI1Summary: ACBI1 is a potent, technology-based BAFATPase subunit and degrader.
- BA2740 3BDOSummary: 3BDO is a new type of activator.
- BA2741 APTO-253Summary: APTO-253 (LOR-253) is a small molecule that inhibits expression, stabilizes G-quadruplex DNA and induces cell cycle arrest and apoptosis in AML cells.
- BA2742 AZD5582Summary: AZD5582 is an antagonist.
- BA2743 BarbadinSummary: Barbadin is a selective interaction inhibitor with values of 19.1 μM and 15.6 μM for β-arrestin1 and β-arrestin2, respectively.
- BA2744 TVB-3166Summary: TVB-3166 is an orally effective, reversible and selective fatty acid synthase inhibitor with 42 nM and 81 nM for FASN and cellular palmitate synthesis, respectively.
- BA2745 OctreotideSummary: Octreotide (SMS201-995) is a growth inhibitor receptor agonist and synthetic octapeptide growth inhibitor analog.
- BA2746 DeferoxamineSummary: Deferoxamine (DeferoxamineB) is an iron chelator (binding Fe(III) and many other metal cations) that is widely used to reduce iron accumulation and deposition in tissues.
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BA2747 MRT-2359Summary: MRT-2359 is a potent, orally active and selective degrader (>30nM and <300nM) that specifically induces protein translation-dependent apoptosis.