Signaling pathways
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BA2719 DT2216Summary: DT2216 is an effective, selective (family member) degrader of a class. - BA2722 TAK-243Summary: TAK-243 (MLN7243) is a first-of-its-kind, selective ubiquitin-activating enzyme, inhibitor.
- BA2723 AZD-7648Summary: AZD-7648 is a selective and orally effective inhibitor.
- BA2724 ICG-001Summary: ICG-001 specifically binds CREB protein to act.
- BA2725 C188-9Summary: C188-9 (TTI-101) is an inhibitor.
- BA2726 dBET6Summary: dBET6 is a highly efficient, selective, cell-permeable, ligand- and ligand-linked PROTAC.
- BA2727 L-AsparaginaseSummary: L-Asparaginase (L-ASNase) is a deamidase that catalyzes the hydrolysis of L-asparagine and L-glutamine and can be used in acute lymphoblastic leukemia.
- BA2728 FB23-2Summary: FB23-2 is a potent and selective inhibitor of mRNAN-methyladenine demethylase.
- BA2729 BrusatolSummary: Brusatol (NSC172924) is a unique pathway inhibitor that sensitizes a wide range of cancer cells to Cisplatin and other chemotherapeutically active molecules.
- BA2730 GSK2795039Summary: GSK2795039 is a NADPH oxidase 2 inhibitor that averaged 6 in different cell-free assays.