Signaling pathways
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BA2746 Deferoxamine5 CitationSummary: Deferoxamine (DeferoxamineB) is an iron chelator (binding Fe(III) and many other metal cations) that is widely used to reduce iron accumulation and deposition in tissues. -
BA2747 MRT-2359Summary: MRT-2359 is a potent, orally active and selective degrader (>30nM and <300nM) that specifically induces protein translation-dependent apoptosis. -
BA2748 DegarelixSummary: Degarelix is a competitive, reversible gonadotropin-releasing hormone receptor antagonist. -
BA2749 CWI1-2Summary: CWI1-2 is an inhibitor. -
BA2750 MS177Summary: MS177 is an effective and fast acting degradant. -
BA2751 CTBSummary: CTB is an activator of p300 histone acetyltransferase. -
BA2752 AC-4-130Summary: AC-4-130 is a potent structural domain inhibitor. -
BA2753 SD-36Summary: SD-36 is an effective degradant (=~50nM) with high selectivity compared to other members. -
BA2754 RMC-6291Summary: RMC-6291 is an orally effective covalent inhibitor. -
BA2755 MilademetanSummary: Milademetan (DS-3032) is a specific, orally active inhibitor for acute myeloid leukemia and solid tumors.

