Signaling pathways
- BA2748 DegarelixSummary: Degarelix is a competitive, reversible gonadotropin-releasing hormone receptor antagonist.
- BA2749 CWI1-2Summary: CWI1-2 is an inhibitor.
- BA2750 MS177Summary: MS177 is an effective and fast acting degradant.
- BA2751 CTBSummary: CTB is an activator of p300 histone acetyltransferase.
- BA2752 AC-4-130Summary: AC-4-130 is a potent structural domain inhibitor.
- BA2753 SD-36Summary: SD-36 is an effective degradant (=~50nM) with high selectivity compared to other members.
- BA2754 RMC-6291Summary: RMC-6291 is an orally effective covalent inhibitor.
- BA2755 MilademetanSummary: Milademetan (DS-3032) is a specific, orally active inhibitor for acute myeloid leukemia and solid tumors.
- BA2756 ONC212Summary: ONC212, a fluorinated ONC201 analog, is a promising anticancer agent and selective agonist.
- BA2757 STL127705Summary: STL127705 is a potent inhibitor of Ku70/80 heterodimeric proteins.