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BC-LI-0186

Catalog No.
BA7168
BC-LI-0186 is a potent and selective inhibitor of the interaction of leucine tRNA synthetase with the related GTP-binding protein D (RagD) (=46.11 nM).
Grouped product items
SizePriceStock Qty
1mL(10 mM in DMSO)
$89.00
Ship with 10-15 days
5mg
$81.00
Ship with 10-15 days
10mg
$135.00
Ship with 10-15 days
25mg
$297.00
Ship with 10-15 days
50mg
$468.00
Ship with 10-15 days
100mg
$720.00
Ship with 10-15 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

BC-LI-0186 is a potent and selective inhibitor of the interaction of leucine tRNA synthetase with the related GTP-binding protein D (RagD) (=46.11 nM).BC-LI-0186 competes with the RagD interaction site of LRS (=42.1 nM) and has no effect on LRS-vps34, LRS-eprs, RagB- RagD conjugation, and mTORC1 complex formation without effect.BC-LI-0186 effectively inhibited the activity of tumor-associated mutants and the growth of rapamycin-resistant cancer cells.BC-LI-0186 can be used in lung cancer related studies.

Chemical Properties

Physical AppearanceA solid
Storage-20°C
M.Wt429.53
Cas No.695207-56-8
FormulaC22H27N3O4S
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.