B-Raf inhibitor 1
Catalog No.
B1172
Potent and selective B-Raf inhibitor
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B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 478.94 |
| Cas No. | 1093100-40-3 |
| Formula | C26H19ClN8 |
| Solubility | ≥47.9 mg/mL in DMSO; insoluble in H2O; ≥5.88 mg/mL in EtOH with ultrasonic |
| Chemical Name | 1-N-(4-chlorophenyl)-6-methyl-5-N-[3-(7H-purin-6-yl)pyridin-2-yl]isoquinoline-1,5-diamine |
| SDF | Download SDF |
| Canonical SMILES | Cc(ccc1c2ccnc1Nc(cc1)ccc1Cl)c2Nc1ncccc1-c1ncnc2c1[nH]cn2 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
