Arctigenin
Catalog No.
N2399
Anti-inflammatory, antiproliferative
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Antioxidant, anti-inflammatory, antiproliferative and antiviral agent. Inhibits LPS-induced iNOS expression via inhibition of IκBα phosphorylation and p65 nuclear translocation (IC50 = 10 nM). Inhibits HIV-1 replication in vitro. Also potently inhibits MKK1 (MEK1) (IC50 = 0.5 nM) and provides neuroprotection by binding to kainate receptors.
| Physical Appearance | A solid |
| Storage | Desiccate at -20°C |
| M.Wt | 372.41 |
| Cas No. | 7770-78-7 |
| Formula | C21H24O6 |
| Synonyms | (-)-Arctigenin |
| Solubility | insoluble in H2O; insoluble in EtOH; ≥17.2 mg/mL in DMSO |
| Chemical Name | (3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one |
| SDF | Download SDF |
| Canonical SMILES | COc(ccc(C[C@@H](CO1)[C@@H](Cc(cc2)cc(OC)c2O)C1=O)c1)c1OC |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
