AQP4 (201-220)
Catalog No.
C8726
Can induce experimental autoimmune encephalomyelitis (EAE)
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AQP4 (201-220) (CAS No.: 2104700-59-4) is an encephalitogenic epitope of aquaporin-4 (AQP4) that can induce experimental autoimmune encephalomyelitis (EAE), characterized by midline brain lesions, retinal lesions, and lesions at the gray/white matter junction of the spinal cord. AQP4 is the target antigen in neuromyelitis optica (NMO). In research, AQP4 (201-220) is commonly used to induce EAE models to investigate the pathogenesis of autoimmune diseases and potential therapeutic strategies. The dose or concentration used in experiments usually depends on the experimental design and research objectives.
| M.Wt | 2151.4 |
| Cas No. | 2104700-59-4 |
| Formula | C97H143N27O27S |
| Chemical Name | L-histidyl-L-leucyl-L-phenylalanyl-L-alanyl-L-isoleucyl-L-asparaginyl-L-tyrosyl-L-threonylglycyl-L-alanyl-L-seryl-L-methionyl-L-asparaginyl-L-prolyl-L-alanyl-L-arginyl-L-seryl-L-phenylalanylglycyl-L-proline |
| SDF | Download SDF |
| Canonical SMILES | OC(C=C1)=CC=C1C[C@H](NC([C@H](CC(N)=O)NC([C@H]([C@@H](C)CC)NC([C@H](C)NC([C@@H](NC([C@H](CC(C)C)NC([C@@H](N)CC2=CN=CN2)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](CCSC)C(N[C@@H](CC(N)=O)C(N4[C@@H](CCC4)C(N[C@@ |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |