Anti-XRCC4 (7C10) Mouse Monoclonal Antibody
Catalog No.
MA5728
Anti-XRCC4 (7C10) Mouse Monoclonal Antibody
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Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
7518
X ray repair cross complementing protein 4; DNA repair protein XRCC4; DNA double strand break repair
Mouse
Human, Mouse, Rat
Unconjugated
Calculated MW: 38 kDa; Observed MW: 38-45 kDa
Unmodified
IgG1
Monoclonal Antibody
AP-14F6B8
Liquid
See label
Carrier Not Free
Synthetic Peptide of XRCC4
Affinity Purified
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
WB, IHC-F, IHC-P, ICC/IF, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.