Anti-TGF-β Receptor Antibody (Sotatercept)
Catalog No.
F2093
Anti-TGF-β Receptor Antibody (Sotatercept)
Featured Products
Sotatercept (ACE-011) is a soluble activin receptor 2A (ACVR2A) type IgG Fc fusion protein. By binding to activins and growth differentiation factors, Sotatercept aims to restore the balance between growth-promoting and growth-inhibitory signaling pathways. This property makes Sotatercept potentially useful in a variety of medical areas, including pulmonary hypertension, anemia, bone loss, erythropoiesis, and osteolytic lesions in multiple myeloma (MM).
Dry ice
1001080-50-7
-80°C
2 years
Liquid
1 mg/mL
For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.
CHO
ACE-011, MK-7962
100 mM Pro 20 mM Arg pH 5.0.
Human
Unconjugated
Monoclonal
Protein A
IgG
ELISA, FACS, Kinetics, Functional assay, Animal Model
TGF-β Receptor
Please avoid freeze-thaw cycles.