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Anti-TGF-β Receptor Antibody (Sotatercept)

Catalog No.
F2093
Anti-TGF-β Receptor Antibody (Sotatercept)
Grouped product items
SizePriceStock Qty
100ug
Please inquire
Ship with 3-5 days
1mg
Please inquire
Ship with 3-5 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Sotatercept (ACE-011) is a soluble activin receptor 2A (ACVR2A) type IgG Fc fusion protein. By binding to activins and growth differentiation factors, Sotatercept aims to restore the balance between growth-promoting and growth-inhibitory signaling pathways. This property makes Sotatercept potentially useful in a variety of medical areas, including pulmonary hypertension, anemia, bone loss, erythropoiesis, and osteolytic lesions in multiple myeloma (MM).

Quality Control

Quality Control & DataSheet

View current batch:
 

Shipping

Dry ice

Cas No.

1001080-50-7

Storage

-80°C

Expiration Date

2 years

Form

Liquid

Concentration

1 mg/mL

Reconstitution

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.

Host

CHO

Alternative Names

ACE-011, MK-7962

Buffer System

100 mM Pro 20 mM Arg pH 5.0.

Reactivity

Human

Conjugation

Unconjugated

Clonality

Monoclonal

Purification

Protein A

Isotype

IgG

Application

ELISA, FACS, Kinetics, Functional assay, Animal Model

Target

TGF-β Receptor

Note

Please avoid freeze-thaw cycles.