Anti-Rb Rabbit Polyclonal Antibody
Catalog No.
PA1323
Anti-Rb Rabbit Polyclonal Antibody
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Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo.
5925
RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 106 kDa; Observed MW: 106 kDa
Unmodified
IgG
Polyclonal Antibody
Liquid
See label
Carrier Not Free
The antiserum was produced against synthesized peptide derived from human Retinoblastoma.
Affinity Purified
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
WB, IHC-F, IHC-P, ICC/IF, ELISA
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.