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Anti-Integrin a4/ITGA4/CD49d Antibody (Natalizumab)

Catalog No.
F1885
Anti-Integrin a4/ITGA4/CD49d Antibody (Natalizumab)
Grouped product items
SizePriceStock Qty
100ug
Please inquire
Ship with 3-5 days
1mg
Please inquire
Ship with 3-5 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Natalizumab is a recombinant humanized IgG4 monoclonal antibody that binds to α4β1-integrin and blocks its interaction with vascular cell adhesion molecule 1 (VCAM-1). Natalizumab is used in the study of relapsing-remitting multiple sclerosis and Crohn's disease. Natalizumab also blocks the entry of lymphocytes into the central nervous system, thereby preventing relapses of acute demyelination.

Quality Control

Quality Control & DataSheet

View current batch:
 

M.Wt

146.22 kDa

Shipping

Dry ice

Cas No.

189261-10-7

Storage

-80°C

Expiration Date

2 years

Form

Liquid

Concentration

See label

Reconstitution

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.

Host

CHO

Alternative Names

Antegran, BG-0002

Buffer System

100 mM Pro 20 mM Arg pH 5.0. No preservative!

Target Accession

P13612

Reactivity

Human

Conjugation

Unconjugated

Clonality

Monoclonal

Isotype

IgG4

Application

ELISA, FACS, Kinetics, Functional assay, Animal Model

Target

Integrin a4 / ITGA4 / CD49d

Note

Please avoid freeze-thaw cycles.