Anisotropine Methylbromide

Anisotropine Methylbromide (CAS No.: 80-50-2) is a synthetic small molecule classified as a quaternary ammonium anticholinergic muscarinic receptor antagonist that is primarily used as a pharmacological tool in gastrointestinal and autonomic physiology research, with functional characterization indicating inhibition of cholinergic signaling that regulates smooth muscle contractility and gastric secretory processes; in biomedical discovery workflows, it is generally positioned within receptor pharmacology and digestive system pathway studies, where it is used to probe muscarinic receptor mediated responses, including downstream calcium dependent signaling and phospholipase C linked mechanisms associated with acetylcholine driven cellular activation, and to distinguish cholinergic components of complex tissue responses in translationally relevant in vitro and ex vivo systems; while publicly accessible source material commonly describes its activity qualitatively rather than with consistently reported standardized potency constants, its experimental effects are typically investigated across nanomolar to micromolar concentration windows in receptor and functional assays depending on model sensitivity and endpoint selection; typical research applications include use in cell based assays of cholinergic signal modulation, organ bath or tissue contractility paradigms, and preclinical animal studies focused on gastrointestinal motility or secretion biology, and in compound profiling panels as a reference antimuscarinic comparator, where the concentrations or doses used in experiments typically depend on specific experimental designs and research objectives.