AMG-1694
Catalog No.
BA7744
AMG-1694 is a potent glucokinase-glucokinase regulatory protein disruptor.
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AMG-1694 is a potent glucokinase-glucokinase regulatory protein disruptor.AMG-1694 promotes dissociation of the GK-GKRP complex at a value of 7 nM, indirectly increasing GKase activity.AMG-1694 effectively reverses an inhibitory effect of GKRP on GK activity and promotes GK translocation.AMG-1694 normalizes blood glucose levels in several rodent diabetic models to normalize blood glucose levels and can only lower blood glucose in diabetic patients but not in animals with normal blood glucose.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 533.63 |
| Cas No. | 1361217-07-3 |
| Formula | C23H30F3N3O4S2 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |