ABBV-744
Catalog No.
BA1895
ABBV-744 is a first-of-its-kind, orally active and selective BDII structural domain of the BET family of proteins.
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ABBV-744 is a first-of-its-kind, orally active and selective BDII structural domain of the BET family of proteins with values of 4-18 nM for BRD2, BRD3, BRD4, and BRDT.ABBV-744 is predominantly metabolized by and possesses properties similar to those of active molecules, which can be used to study its antitumor efficacy and tolerability.
| Physical Appearance | A solid |
| Storage | 4°C |
| M.Wt | 491.55 |
| Cas No. | 2138861-99-9 |
| Formula | C28H30FN3O4 |
| Chemical Name | N-ethyl-4-(2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide |
| Canonical SMILES | O=C(NCC)C1=CC=2C(=CN(C(=O)C2N1)C)C=3C=C(C=CC3OC=4C(=CC(F)=CC4C)C)C(O)(C)C |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |