8-Methoxypsoralen
Catalog No.
N1305
CYP inhibitor
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8-Methoxypsoralen (CAS 298-81-7) is a tricyclic furocoumarin compound, functioning as a suicide inhibitor of cytochrome P450 (CYP) enzymes. By irreversibly binding to CYP active sites, 8-Methoxypsoralen effectively impedes enzymatic activity, thereby modulating metabolic pathways involving CYPs. Comparative studies indicate that 8-Methoxypsoralen demonstrates greater inhibitory potency against CYP enzymes than related furanocoumarins such as 5-MOP, 5-hydroxypsoralen, dihydro-8-MOP, and psoralen. This compound is widely employed in the investigation of CYP-mediated metabolism, drug-drug interactions, and enzyme inhibition mechanisms.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 216.19 |
| Cas No. | 298-81-7 |
| Formula | C12H8O4 |
| Synonyms | xanthotoxin;methoxsalen;ammoidin |
| Solubility | insoluble in H2O; insoluble in EtOH; ≥6.5 mg/mL in DMSO |
| Chemical Name | 9-methoxyfuro[3,2-g]chromen-7-one |
| SDF | Download SDF |
| Canonical SMILES | COc(c([o]cc1)c1cc1C=C2)c1OC2=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
