6α-methyl-11β-Hydroxyprogesterone
6α-Methyl-11β-hydroxyprogesterone is a synthetic glucocorticoid which has been used in the treatment of inflammatory eye diseases. 6α-Methyl-11β-hydroxyprogesterone is a corticosteroid with anti-inflammatory properties which has been discontinued in the United States. The structure of 6α-Methyl-11β-hydroxyprogesterone is very similar to progesterone. Neither progestogenic nor androgenic activity has been demonstrated for or attributed to medrysone [1, 2].
References:
[1] The dictionary of drugs: chemical data: chemical data, structures and bibliographies[M]. Springer, 2014.
[2] SPAETH G L. Hydroxymethylprogesterone: An anti-inflammatory steroid without apparent effect on intraocular pressure[J]. Archives of Ophthalmology, 1966, 75(6): 783-787.
| Physical Appearance | A crystalline solid |
| Storage | Store at -20°C |
| M.Wt | 344.5 |
| Cas No. | 2668-66-8 |
| Formula | C22H32O3 |
| Synonyms | NSC 63278,Visudrisone |
| Solubility | ≤1mg/ml in ethanol;1mg/ml in methanol;1mg/ml in acetonitrile |
| Chemical Name | (6α,11β)-11-hydroxy-6-methyl-pregn-4-ene-3,20-dione |
| SDF | Download SDF |
| Canonical SMILES | C[C@@]12[C@](CC[C@@H]2C(C)=O)([H])[C@]3([H])C[C@H](C)C4=CC(CC[C@]4(C)[C@@]3([H])[C@@H](O)C1)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Purity ≥95.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
