2,2':5',2''-Terthiophene
2,2':5',2''-Terthiophene (CAS No.: 1081-34-1) is an oligomeric thiophene derivative widely utilized in life sciences and materials-oriented research due to its distinctive physicochemical and bioactive properties. As a member of the oligothiophene class, it serves as a valuable molecular scaffold in studies exploring interactions with biological systems, where it has been reported to modulate specific signaling pathways and influence enzymatic activity, thereby functioning as a tool compound for probing molecular mechanisms underlying cellular processes. Although precise molecular targets remain context-dependent, investigations in biochemical and cellular models suggest that its activity may involve interference with oxidative processes and signal transduction pathways, typically observed within the nanomolar to low micromolar concentration range depending on assay conditions and model systems. In addition to its biological relevance, this compound is extensively employed as a building block in the synthesis of polythiophene-based materials, bridging research in organic electronics with biointerface studies. Its dual utility supports applications in mechanistic studies of disease-related pathways, high-content screening assays, and the development of functional biomaterials, with experimental concentrations or dosing regimens varying according to specific research objectives and system requirements.
| Physical Appearance | Solid |
| Storage | -20°C |
| M.Wt | 248.39 |
| Cas No. | 1081-34-1 |
| Formula | C12H8S3 |
| Synonyms | α-Terthiophene;α-Terthienyl;Trithiophene |
| Solubility | ≥42.5 mg/mL in DMSO; ≥14 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | 2,2':5',2''-terthiophene |
| Canonical SMILES | C1(C2=CC=C(C3=CC=CS3)S2)=CC=CS1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure








