Signaling pathways
- BA2625 Val-Cit-PAB-MMAESummary: Val-Cit-PAB-MMAE is part of the antibody-coupled active molecule.
- BA2626 PC5-VC-PAB-MMAESummary: PC5-VC-PAB-MMAE consists of (PC5-VC-PAB) and MMAE, a potent microtubule inhibitor.
- BA2627 McMMAFSummary: McMMAF is composed of the highly efficient microtubule inhibitor MonomethylF (MMAF) coupled with the protecting group maleimidocaproyl, which can be used as the active molecular linker.
- BA2628 SMCC-DM1Summary: SMCC-DM1 (DM1-SMCC) is formed by linking the linkerSMCC to the toxic molecule DM1 and can be used to prepare antibody-coupled active molecules.
- BA2629 MC-Val-Cit-PAB-MMAFSummary: MC-Val-Cit-PAB-MMAF (Vc-MMAF) is an antibody-coupled compound.
- BA2630 DBCO-PEG4-VC-PAB-MMAESummary: DBCO-PEG4-VC-PAB-MMAE consists of (DBCO-PEG4-VC-PAB) and the microtubule protein polymerization inhibitor MMAE.
- BA2631 Mal-VC-PAB-DM1Summary: Mal-VC-PAB-DM1 is part of an antibody-coupled active molecule.
- BA2632 SPDB-DM4Summary: The SPDB-DM4 is part of the ADC.
- BA2633 MC-VA-PAB-ExatecanSummary: MC-VA-PAB-Exatecan is part of an antibody-coupled active molecule.
- BA2634 Mc-VC-PAB-SN38Summary: Mc-VC-PAB-SN38 consists of degradable (cleavable) (Mc-VC-PAB) and SN38, a DNA topoisomerase I inhibitor.