Signaling pathways
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BA2648 Mal-PEG8-Val-Cit-PAB-MMAESummary: Mal-PEG8-Val-Cit-PAB-MMAE is part of the antibody-coupled active molecule ADC. - BA2649 DBCO-PEG4-VA-PBDSummary: DBCO-PEG4-VA-PBD is an antibody-coupled active molecule consisting of the antitumor antibiotic Pyrrolobenzodiazepine (PBD) linked to DBCO-PEG4-VA.
- BA2650 MAL-di-EG-Val-Cit-PAB-MMAESummary: It is composed of MonomethylE (MMAE), a highly potent microtubule inhibitor, coupled with the peptide linker MAL-di-EG-Val-Cit-PAB.
- BA2651 MC-SN38Summary: MC-SN38 is an active molecular coupler consisting of SN38, a potent microtubule disruptor, and a non-cleavable MClinker for the synthesis of antibody active molecular couplers (ADCs).
- BA2652 MMAE-SMCCSummary: MMAE-SMCC is an antibody-coupled active molecule consisting of MMAE, a potent inhibitor of mitotic and microtubule proteins, and SMCC, a connector.
- BA2653 endo-BCN-PEG4-Val-Cit-PAB-MMAESummary: endo-BCN-PEG4-Val-Cit-PAB-MMAE can be used to synthesize antibody-coupled active molecules (ADCs).
- BA2654 Lys-SMCC-DM1Summary: Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is a coupler that inhibits microtubule protein polymerization.
- BA2655 PB038Summary: PB038 is a coupler of the ADC drug toxin molecule and linker.
- BA2656 SuO-Glu-Val-Cit-PAB-MMAESummary: SuO-Glu-Val-Cit-PAB-MMAE (NHS-Glutarate-Val-Cit-PAB-MMAE) consists of degradable (cleavable) (SuO-Glu-Val-Cit-PAB) and MMAE, which is a potent microtubule (tubulin) inhibitor.
- BA2657 OSu-PEG4-VC-PAB-MMAESummary: OSu-PEG4-VC-PAB-MMAE was involved in the synthesis of GDP-FAmPMMAE (methyl auristatin E).