Signaling pathways
- BA2640 Gly3-VC-PAB-MMAESummary: Gly3-VC-PAB-MMAE consists of degradable (cleavable) (Gly3-VC-PAB) and MMAE, a potent microtubule (tubulin) inhibitor.
- BA2641 MC-VA-PABC-MMAESummary: MC-VA-PABC-MMAE is part of an antibody-coupled active molecule.
- BA2642 MC-betaglucuronide-MMAE-1Summary: MC-betaglucuronide-MMAE-1 is part of.
- BA2643 DM21Summary: DM21 is a cleavable affix of an ADC active molecule and linker (ADClinker).
- BA2645 Mal-PEG4-VC-PAB-DMEA-PNU-159682Summary: Mal-PEG4-VC-PAB-DMEA-PNU-159682 is an active molecule-coupling consisting of the ADC connector Mal-PEG4-VC-PAB and the potent ADC cytotoxin DMEA-PNU-159682.
- BA2646 Amino-PEG4-Val-Cit-PAB-MMAESummary: Can be used to synthesize antibody-coupled reactive molecules (ADCs).
- BA2647 DBCO-PEG4-Val-Cit-PAB-MMAFSummary: DBCO-PEG4-Val-Cit-PAB-MMAF consists of degradable (cleavable) 4-unit PEG-containing (DBCO-PEG4-Val-Cit-PAB) and MMAF.
- BA2648 Mal-PEG8-Val-Cit-PAB-MMAESummary: Mal-PEG8-Val-Cit-PAB-MMAE is part of the antibody-coupled active molecule ADC.
- BA2649 DBCO-PEG4-VA-PBDSummary: DBCO-PEG4-VA-PBD is an antibody-coupled active molecule consisting of the antitumor antibiotic Pyrrolobenzodiazepine (PBD) linked to DBCO-PEG4-VA.
- BA2650 MAL-di-EG-Val-Cit-PAB-MMAESummary: It is composed of MonomethylE (MMAE), a highly potent microtubule inhibitor, coupled with the peptide linker MAL-di-EG-Val-Cit-PAB.