Signaling pathways
- BA2638 CL2-SN-38Summary: CL2-SN-38 is coupled to hRS7, an anti-Trop-2-humanized antibody.
- BA2639 Mc-MMAESummary: Mc-MMAE is the protecting group (maleoyliminohexanoyl) conjugated to MMAE.
- BA2640 Gly3-VC-PAB-MMAESummary: Gly3-VC-PAB-MMAE consists of degradable (cleavable) (Gly3-VC-PAB) and MMAE, a potent microtubule (tubulin) inhibitor.
- BA2641 MC-VA-PABC-MMAESummary: MC-VA-PABC-MMAE is part of an antibody-coupled active molecule.
- BA2642 MC-betaglucuronide-MMAE-1Summary: MC-betaglucuronide-MMAE-1 is part of.
- BA2643 DM21Summary: DM21 is a cleavable affix of an ADC active molecule and linker (ADClinker).
- BA2644 Mal-PEG2-VCP-EribulinSummary: Mal-PEG2-VCP-Eribulin is coupled from (Mal-PEG2-VCP) and...
- BA2645 Mal-PEG4-VC-PAB-DMEA-PNU-159682Summary: Mal-PEG4-VC-PAB-DMEA-PNU-159682 is an active molecule-coupling consisting of the ADC connector Mal-PEG4-VC-PAB and the potent ADC cytotoxin DMEA-PNU-159682.
- BA2646 Amino-PEG4-Val-Cit-PAB-MMAESummary: Can be used to synthesize antibody-coupled reactive molecules (ADCs).
- BA2647 DBCO-PEG4-Val-Cit-PAB-MMAFSummary: DBCO-PEG4-Val-Cit-PAB-MMAF consists of degradable (cleavable) 4-unit PEG-containing (DBCO-PEG4-Val-Cit-PAB) and MMAF.