Signaling pathways
- BA2668 DM4-SMCCSummary: DM4-SMCC is an antibody-coupled active molecule.
- BA2669 Py-MAA-Val-Cit-PAB-MMAESummary: Py-MAA-Val-Cit-PAB-MMAE is a drug-linker coupler for ADCs, which consists of MMAE linked to Py-MAA-Val-Cit-PAB.
- BA2670 MC-DM1Summary: MC-DM1 is formed by linkerMC and toxic molecule DM1 linkage, which can be used to prepare antibody-coupled active molecules.
- BA2671 DBCO-PEG4-VC-PAB-DMEA-PNU-159682Summary: DBCO-PEG4-VC-PAB-DMEA-PNU-159682, an active molecule-coupling consisting of the ADC connector DBCO-PEG4-VC-PAB and the potent ADC cytotoxin DMEA-PNU-159682.
- BA2672 Acetylene-linker-Val-Cit-PABC-MMAESummary: Acetylene-linker-Val-Cit-PABC-MMAE (LCB14-0602) consists of (Acetylene-linker-Val-Cit-PABC) and MMAE, a potent microtubule (tubulin) inhibitor.
- BA2673 SPP-DM1Summary: SPP-DM1 is part of the antibody-coupled active molecule.
- BA2674 MC-VC-PABC-DNA31Summary: MC-VC-PABC-DNA31 is part of the antibody-coupled active molecule.
- BA2675 Vc-MMADSummary: Vc-MMAD consists of the linker (Val-Cit) and the microtubule inhibitor MMAD.
- BA2676 Val-Ala-PAB-MMAESummary: Val-Ala-PAB-MMAE is a Drug-LinkerConjugatesforADC.
- BA2677 DIBAC-GGFG-NH2CH2-DxdSummary: DIBAC-GGFG-NH2CH2-Dxd are derivatives, which are linkage carriers for protein-active molecule couplers.