Bioactive Compounds
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BA2983 BatabulinSummary: Batabulin (T138067) is an antitumor agent that covalently and selectively binds to a subset of beta-microtubule protein isoforms, thereby disrupting microtubule polymerization. - BA1817 MorphothiadinSummary: Morphothiadin is a potent inhibitor of wild-type and adefovir-resistant replication.
- BA2973 IndibulinSummary: Indibulin (ZIO301), an orally effective synthetic inhibitor with good anticancer activity and minimal neurotoxicity.
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BA1816 EntecavirSummary: Potent and selective inhibitor of HBV DNA polymerase (reverse transcriptase), with core bioactivity of inhibiting replication of chronic hepatitis B virus (HBV). - BA2942 LCH-7749944Summary: LCH-7749944 (GNF-PF-2356) is a potent inhibitor.
- BA1815 RG7834Summary: RG7834 (RO7020322) is a highly selective, orally available inhibitor.
- BA2911 IrigeninSummary: Irigenin is a lead compound that mediates its anti-metastatic effects by specifically and selectively blocking the ExtraDomainA (EDA) domain on the C-C loop and at integrin binding sites.
- BA1814 SelgantolimodSummary: Selgantolimod (GS-9688) is orally active.
- BA2854 BTT-3033Summary: BTT-3033 is an orally active conformation-selective (130nM) inhibitor that binds to the α2Idomain.
- BA1813 BulevirtideSummary: Bulevirtide (MyrcludexB) is an inhibitor and is a linear lipopeptide.