Signaling pathways
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BA4209 Kira8Summary: Kira8 (AMG-18) is a monoselective inhibitor that can be denatured to attenuate activity. - BA4210 GSK2850163Summary: GSK2850163 is a novel inositol-requiring enzyme-1α inhibitor.
- BA4211 MKC3946Summary: MKC3946 is a potent inhibitor.
- BA4212 IXA6Summary: IXA6 is a novel agonist.
- BA4213 MKC9989Summary: MKC9989 is an inhibitor.
- BA4214 KIRA-7Summary: KIRA-7 is an imidazopyrazine compound that binds to the kinase (for 110 nM) to inhibit its RNase activity in a metastable manner.
- BA4215 Z4PSummary: Z4P is an inhibitor that penetrates the blood-brain barrier.
- BA4216 AZ82Summary: A selective inhibitor of the kinesin-like protein KIFC1.
- BA4217 MC-Val-Cit-PAB-IspinesibSummary: MC-Val-Cit-PAB-Ispinesib is a potent inhibitor.
- BA4218 LitronesibSummary: Litronesib (LY2523355) is a selective inhibitor of mitosis-specific motor proteins.