Signaling pathways
- BA7389 SENP1-IN-1Summary: SENP1-IN-1 is an inhibitor of specific de-SUMOized proteases.
- BA7390 EN450Summary: EN450 is a targeted cysteine-responsive covalent molecular gel degrader.
- BA7391 WS-383Summary: WS-383 is a potent, selective and reversible interaction inhibitor.
- BA7392 Cbl-b-IN-5Summary: Cbl-b-IN-5 is an inhibitor (=3-10 μM).
- BA7393 BC-1382Summary: BC-1382 is a potent ubiquitin E3 ligase inhibitor that specifically disrupts the HECTD2/PIAS1 interaction (≈5 nM).
- BA7394 SCFSkp2-IN-2Summary: SCFSkp2-IN-2 is an inhibitor.
- BA7395 UC-764864Summary: UC-764864 is an inhibitor.
- BA7396 Smurf1-IN-1Summary: SMURF1-IN-1 is an orally active selective inhibitor of specific E3 ubiquitin protein ligase 1.
- BA7397 RugonersenSummary: Rugonersen (RG6091; RO7248824) is a locked nucleic acid (LNA)-modified antisense oligonucleotides (ASOs) that reduces ubiquitin protein ligase E3A (UBE3A) silencing.
- BA7398 BAY-85-8501Summary: BAY-85-8501 is a potent, selective inhibitor of human neutral lipase.