Signaling pathways
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BA4359 PamiparibSummary: Pamiparib (BGB-290) is a potent, highly selective inhibitor with oral activity. - BA4360 RBN012759Summary: RBN012759 is a potent, selective and orally active inhibitor with values <3nM, 300-fold more selective than for monoPARPs and 1000-fold more selective than for polyPARPs.
- BA4361 SK-575Summary: SK-575 is a highly efficient and specific degrader of protein hydrolysis-targeted chimeras.
- BA4362 RBN-3143Summary: RBN-3143 is a potent inhibitor of NAD+ competitive catalysis.
- BA4363 AZ9482Summary: AZ9482 is a triple inhibitor of PARP1/2/6.
- BA4364 SenaparibSummary: Senaparib (IMP4297) is a potent, selective, and orally effective inhibitor.
- BA4365 iRucaparib-AP6Summary: iRucaparib-AP6 is a highly efficient and specific degrading agent.
- BA4366 VenadaparibSummary: Venadaparib (IDX-1197) is a potent, selective and orally active inhibitor.
- BA4367 BRCA1-IN-2Summary: BRCA1-IN-2 is an inhibitor of protein-protein interactions (PPIs) with cell permeability.
- BA4368 OUL35Summary: OUL35 (NSC39047) is a selective inhibitor.