Signaling pathways
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BA5557 MavoglurantSummary: Mavoglurant (AFQ056) is a potent, selective, non-competitive and orally active antagonist. - BA5558 LY2794193Summary: LY2794193 is a potent and selective receptor agonist.
- BA5559 JNJ-40411813Summary: JNJ-40411813 (ADX-71149) is a novel orthosteric modulator of the metabotropicGlutamate2receptor.
- BA5560 JNJ-46778212Summary: JNJ-46778212 (VU0409551) is an orthotropic modifier.
- BA5561 RO0711401Summary: RO0711401 is a selective orthosteric modulator of receptors with oral activity.
- BA5562 VU0650786Summary: VU0650786 is a potent, CNS-transmitting, selective glutamate receptor subtype 3 negative modulator.
- BA5563 BMS-984923Summary: BMS-984923 is a potent silent allosteric modulator with good affinity (K=0.6nM), good oral bioavailability and blood-brain barrier permeability.
- BA5564 VU6005649Summary: A CNS-permeable receptor agonist.
- BA5565 ADX88178Summary: ADX88178 is a potent metabotropic glutamate receptor 4 orthosteric modulator (PAM).
- BA5566 VU0422288Summary: VU0422288 (ML396) is an orthosteric modulator of the type III mGlu receptor (mGlus).