Signaling pathways
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BA5577 HTL14242Summary: HTL14242 (HTL0014242) is an advanced, orally active negatively variable modulator with summed values of 9.3 and 9.2, respectively. - BA5578 FPTQSummary: FPTQ is a potent antagonist with inhibitory values of 6 nM and 1.4 nM in human and mouse, respectively.
- BA5579 JNJ-46281222Summary: JNJ-46281222 is a selective metabolic glutamate 2 efficient PAM (orthosteric modifier).
- BA5580 FTIDCSummary: FTIDC is an oral, non-competitive, selective metabotropic glutamate receptor 1 antagonist.
- BA5581 ML353Summary: ML353 is a selective ligand for silencing alteration modifier (SAM).
- BA5582 VU0080241Summary: VU0080241 is a metabotropic glutamate receptor 4 orthosteric modulator (PAM).
- BA5583 LY2812223Summary: LY2812223 is a potent, functionally selective receptor agonist with binding affinity for mGlu and mGlu.
- BA5584 LSN2463359Summary: LSN2463359 is an orthosteric modulator of metabotropic glutamate 5.
- BA5585 VU6010572Summary: The VU6010572 is an efficient selective negative variance modulator.
- BA5586 BMT-145027Summary: BMT-145027 is an orthosteric modulator and has no intrinsic agonist activity.