Signaling pathways
- BA3279 7-epi-IsogarcinolSummary: 7-epi-Isogarcinol is a polycyclic polyisoprenoylresorcinol (PPAP) with moderate antiproliferative activity.
- BA3280 FlurochloridoneSummary: Flurochloridone (R-40244) is a selective pre-emergent persistent herbicide.
- BA3281 OsmundacetoneSummary: Osmundacetone is a natural product with neuroprotective and anti-apoptotic effects.
- BA3282 BiflorinSummary: It has antibacterial, antitumor, anti-inflammatory and antimutagenic activities.
- BA3283 HG-7-85-01Summary: HG-7-85-01 inhibits the T315I mutant kinase with little or no inhibition of other kinases (IC>2 μM).
- BA3284 PARP-1-IN-3Summary: PARP-1-IN-3, a benzamide derivative, is a potent inhibitor with values of 0.25 nM and 2.34 nM for PARP-1 and PARP-2, respectively.
- BA3285 TomentosinSummary: Tomentosin is an anti-inflammatory sesquiterpene lactone that can be isolated from the Caspian Sea cyclamen.
- BA3286 FascaplysinSummary: Fascaplysin is an anti-microbial and cytotoxic red pigment that can come from marine sponges.
- BA3287 PI3Kδ-IN-16Summary: PI3Kδ-IN-16 is a potent and selective inhibitor.
- BA3289 UK-101Summary: UK-101 is a potent and selective inhibitor of immunoproteasome β1i (=104 nM).