Signaling pathways
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BA2832 E64FC26Summary: E64FC26 is a potent pan-inhibitor of the protein disulfide bond isomerase family, with 1.9, 20.9, 25.9, 16.3 and 25.4 μM for PDIA1, PDIA3, PDIA4, TXNDC5 and PDIA6, respectively. - BA2833 MMRi62Summary: MMRi62 is an iron death inducer that targets (oncogene p53 negative regulator).
- BA2834 JQAD1Summary: JQAD1 is CRBN-dependent and selectively targeted for degradation.
- BA2835 NitrochinSummary: Nitrochin (4-NQO) is a chemical carcinogen.
- BA2836 RobininSummary: Robinin, a flavonoid that can be extracted from purple-red cowpea leaves, inhibits the TGF-β, TLR4/NF-κB, and TLR2-PI3k-AKT signaling pathways and exerts anti-inflammatory and antitumor effects.
- BA2838 BendamustineSummary: Bendamustine (SDX-105 free base), a purine analog, is a cross-linking agent.
- BA2839 NBDHEXSummary: NBDHEX is a potent inhibitor of glutathione S-transferase P1-1.
- BA2840 TomatineSummary: Tomatine is a glycoside alkaloid found in the tomato plant (Mill.).
- BA2841 L67Summary: L67 (DNALigaseInhibitor) is a competitive DNA ligase inhibitor that potently inhibits DNA ligases I and III (both 10 μM).
- BA2842 LobaplatinSummary: Lobaplatin (D-19466) is an diastereomeric mixture of platinum(II) complexes.