Signaling pathways
-
BA2341 DC0-NH2Summary: DC0-NH2 is the effector fraction and is an analog of DC1 with higher stability. -
BA2342 SGD-1882Summary: SGD-1882 is a cytotoxic DNA minor groove crosslinker. -
BA2343 DM1-SMeSummary: DM1-SMe is an unbound form of Maytansinoid in IMGN901. -
BA2345 Cyclopropaneacetamide-ExatecanSummary: Cyclopropaneacetamide-Exatecan (Compound 2-A) is an Exatecan analog. -
BA2346 DM4-SMe -
BA2347 AminohexylgeldanamycinSummary: Aminohexylgeldanamycin (AHGDM), a derivative of Geldanamycin, is a heat shock protein 90 inhibitor. -
BA2348 S-Me-DM4Summary: S-Me-DM4 is a metabolite of a portion of DM4 produced by the intracellular enzyme S-methylation. -
BA2350 HemiasterlinSummary: Hemiasterlin ((-)-Hemiasterlin) is an anti-mitotic marine natural product with potent anti-cancer properties. -
BA2354 TAM470Summary: TAM470 is a novel cytolysin that inhibits microtubule protein aggregation and microtubule depolymerization. -
BA2355 INX-SM-56Summary: INX-SM-56 is a toxin molecule that can be used to synthesize anti-body reactive molecular couplers.

