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Signaling pathways

Items 1021-1030 of 7903

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  1. VU0467154
    BA5489 VU0467154
    Summary: VU0467154 is a positive modulator of M4 muscarinic acetylcholine receptors.
  2. VU0453595
    BA5490 VU0453595
    Summary: VU0453595 is a highly selective, systemically active orthotropic modulator.
  3. Biperiden
    BA5491 Biperiden
    Summary: Biperiden (KL373) is a non-selective muscarinic receptor antagonist that competitively binds to muscarinic receptors, thereby inhibiting acetylcholine and enhancing dopamine signaling in the central nervous system.
  4. TAK-071
    BA5492 TAK-071
    Summary: TAK-071 is a new type of highly efficient and selective ortho-modifier.
  5. Smilagenin
    BA5493 Smilagenin
    Summary: Smilagenin (SMI) is a small molecule steroidal saponin element derived from robinia and geranium that is widely used in the study of chronic neurodegenerative diseases.
  6. VU0119498
    BA5494 VU0119498
    Summary: VU0119498 is a pan-G orthotropic modulator (PAM) with values of 6.04, 6.38 and 4.08 μM, respectively.
  7. VU0238441
    BA5495 VU0238441
    Summary: VU0238441 is a pan-muscarinic acetylcholine receptor-positive altered modulator (PAM).
  8. VU6019650
    BA5496 VU6019650
    Summary: VU6019650 is a potent
  9. VU6028418
    BA5497 VU6028418
    Summary: VU6028418 is a potent, highly selective antagonist with oral activity.
  10. ML380
    BA5498 ML380
    Summary: ML380 is a potent, subtype-selective and blood-brain-barrier-crossing orthosteric modulator (PAM) with values of 190 and 610 nM for human and rat M5, respectively.

Items 1021-1030 of 7903

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Category
  1. NF-κB Related7item
  2. Apoptosis60item
  3. Cell Cycle24item
  4. Endocrinology and Hormones2item
  5. GPCR36item
  6. Immunology293item
  7. JAK46item
  8. Membrane Transporter21item
  9. Metabolic Enzyme43item
  10. Other Signal Transduction475item
  11. Proteases2item
  12. Stem Cell10item
  13. Neuroscience46item
  14. TGF-β10item
  15. Tyrosine Kinase63item
  16. Ubiquitination1 item
  17. Anti-infection9item
  18. Natural Products1 item
  19. Apoptosis/Autophagy24item
  20. Immunology/Inflammation21item
  21. PI3K/Akt/mTOR Signaling4item
  22. Cell Cycle/DNA Damage15item
  23. GPCR/G Protein14item
  24. Metabolic Enzyme/Protease40item
  25. MAPK/ERK Pathway7item
  26. Epigenetics18item
  27. PI3K5item
  28. MAPK3item
  29. JAK/STAT Signaling1 item
  30. Stem Cell/Wnt9item
  31. Mitochondrial Metabolism1 item
  32. Neuronal Signaling1 item
  33. Membrane Transporter/Ion Channel7item
  34. TGF-β/Smad Signaling2item
Specificity
  1. Selective11item
Target
  1. Histone Deacetylases (HDACs)2item
  2. FLT31 item
  3. GSK-31 item
  4. Farnesoid X receptors (FXRs)1 item
  5. VEGFR1 item
  6. c-Kit1 item
  7. p381 item
  8. FGFR1 item
  9. Nrf21 item
  10. TNKS1 item
  11. Toll-like receptors (TLRs)2item
  12. DNA Methyltransferases1 item
  13. PKC1 item
  14. CSF1R1 item
  15. Glutaminases1 item
  16. Cytidine deaminases1 item
  17. Vitamin D receptors (VDRs)1 item
  18. Histone Acetyltransferases (HATs)1 item
  19. Tyrosinases1 item
  20. Pregnane X receptor(PXR)1 item
  21. topoisomerase1 item
  22. IDO1 item
Reported Experiments
  1. Animal Experiments17item
  2. Cell Experiments12item
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