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MEK1/2

Items 11-20 of 37

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  1. U0124
    B6882 U0124
    Summary: Inactive analog of U0126(MEK-1/2 inhibitor), used as a negative control
      <22.63 mg/mL
  2. GDC-0623
    B1135 GDC-0623
    Target: MEK
    Summary: MEK1 inhibitor, potent and ATP-uncompetitive
      insoluble in H2O; ≥16.85 mg/mL
  3. Refametinib
    B1267 Refametinib
    Target: MEK
    Summary: MEK 1/ MEK 2 inhibitor
      insoluble in H2O; ≥151.8 mg/mL
  4. TAK-733
    B1621 TAK-733
    Target: MEK
    Summary: MEK allosteric site inhibitor
      ≥25.2 mg/mL
  5. RO4987655
    B3261 RO4987655
    Summary: MEK inhibitor
      insoluble in H2O; insoluble in EtOH; ≥56.6 mg/mL
  6. AZD8330
    A8374 AZD8330
    Target: MEK
    Summary: MEK 1/2 inhibitor
      ≥23.05 mg/mL
  7. MEK162 (ARRY-162, ARRY-438162)
    A1947 MEK162 (ARRY-162, ARRY-438162)
    Target: MEK
    Summary: MEK1/2 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; insoluble in DMSO
  8. BIX 02188
    A5803 BIX 02188
    Target: MEK
    Summary: MEK5 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥10.3 mg/mL
  9. BIX 02189
    A5801 BIX 02189
    Target: MEK|ERK
    Summary: Selective MEK5 inhibitor
      ≥22.05 mg/mL
  10. PD318088
    A5707 PD318088
    Target: MEK
    Summary: Allosteric MEK1/2 inhibitor, non-ATP competitive
      ≥28.05 mg/mL

Items 11-20 of 37

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