Signaling pathways
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BA2902 PonicidinSummary: Ponicidin (RubescensineB) is a diterpene derived from dong quai with immunomodulatory, anti-inflammatory, antiviral and anticancer properties. - BA2903 SCR130Summary: SCR130 is an SCR7-based inhibitor of DNA non-homologous end joining.
- BA2904 RO8994Summary: A potent and selective MDM2 inhibitor with IC50 of nM (HTRF binding assay) and 20 nM (MTT proliferation assay).
- BA2905 HirudinSummary: Hirudin is an inhibitor with anticoagulant properties.
- BA2906 PicrocrocinSummary: Picrocrocin, a carotenoid found in saffron.
- BA2908 KaranjinSummary: Karanjin is an orally active furanoflavonoid that can be isolated from several legumes.
- BA2909 NSC49652Summary: NSC49652 is a reversible, orally active (p75, also known as NGFR, TNFRSF16 and CD271) agonist.
- BA2910 HelichrysetinSummary: Helichrysetin can be isolated from the flowers.
- BA2911 IrigeninSummary: Irigenin is a lead compound that mediates its anti-metastatic effects by specifically and selectively blocking the ExtraDomainA (EDA) domain on the C-C loop and at integrin binding sites.
- BA2912 PhenoxodiolSummary: Phenoxodiol (Idronoxil) is a synthetic analog of Genestein that activates the mitochondrial system, inhibits (an apoptosis inhibitor), and sensitizes cancer cells to Fas-mediated apoptosis.