Signaling pathways
- BA5698 RO1138452Summary: RO1138452 is a potent and selective prostacyclin receptor antagonist.
- BA5699 TravoprostSummary: Travoprost (Fluprostenolisopropylester), an isopropyl ester precursor, is a high-affinity, selective full prostaglandin receptor agonist.
- BA5700 OmidenepagSummary: Omidenepag (UR-7276) is the pharmacologically active form of OmidenepagIsopropyl, a selective non-prostaglandin receptor agonist with an EC of 1.1 nM.
- BA5701 NTP42Summary: NTP42 is a thromboxane receptor antagonist that antagonizes TP-mediated [Ca] circulation after stimulation of cells with the prostaglandin receptor (TP) agonist U46619 with an IC of 3.278 nM.
- BA5702 TaprenepagSummary: Taprenepag (CP-544326) is a potent and selective prostaglandin agonist.
- BA5703 KAG-308Summary: KAG-308 is a potent, selective, orally available (a prostaglandin E2 receptor subtype) agonist.
- BA5704 MF-766Summary: MF-766 is a potent, selective and orally active antagonist.
- BA5705 VidupiprantSummary: Vidupiprant (AMG853) is a phenylacetic acid derivative and a potent orally active and dual antagonist.
- BA5706 RidogrelSummary: Ridogrel (R68070) is an orally active thromboxane A2 synthase inhibitor and thromboxane A2/prostaglandin endoperoxide receptor blocker.
- BA5707 RalinepagSummary: Ralinepag is a potent, orally available, non-prostaglandin agonist.