Signaling pathways
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BA3530 BenpyrineSummary: Benpyrine is a highly specific inhibitor with oral activity. - BA3531 TNF-α-IN-6Summary: TNF-alpha-IN-6 is an orally potent variant inhibitor.
- BA3532 TebentafuspSummary: Tebentafusp (IMCgp100) is a bispecific fusion protein targeting (a melanoma-associated antigen).
- BA3533 HomoplantagininSummary: Flavonoids with anti-inflammatory and antioxidant activity from Chinese herbs.
- BA3534 AX-024Summary: AX-024 is an orally available, first-in-class interaction inhibitor that selectively inhibits TCR-triggered T cell activation.
- BA3535 FrexalimabSummary: Frexalimab (SAR441344; INX-021) is a monoclonal antibody that targets the ligand.
- BA3536 ElobixibatSummary: Elobixibat (A3309; AZD7806) is an orally effective inhibitor with values of 0.53 nM (human IBAT), 0.13 nM (mouse IBAT), and 5.8 nM (canine IBAT), respectively.
- BA3537 SciadopitysinSummary: Sciadopitysin is a biflavonoid from Ginkgo biloba.
- BA3538 CynaropicrinSummary: Cynaropicrin, a sesquiterpene lactone, inhibits the release of tumor necrosis factor with values of 8.24 and 3.18 μM in murine and human macrophages, respectively.
- BA3539 ApratastatSummary: Apratastat (TMI-005) is an orally potent, non-selective and reversible inhibitor of the release of...