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Biochemical Reagent
Signaling pathways

Signaling pathways

BA5497 VU6028418

Summary: VU6028418 is a potent, highly selective antagonist with oral activity.
BA5498 ML380

Summary: ML380 is a potent, subtype-selective and blood-brain-barrier-crossing orthosteric modulator (PAM) with values of 190 and 610 nM for human and rat M5, respectively.
BA5499 Pentoxyverine

Summary: Pentoxyverine (Carbetapentane) is an orally active receptor agonist with σ1 values of 41nM, 894nM and 75nM in for σ1, σ2 and guinea pig brain membranes, respectively.
BA5500 MK-6884

Summary: MK-6884 is a muscarinic receptor orthosteric modulator (PAM).
BA5501 Solifenacin

Summary: Solifenacin is a novel muscarinic receptor antagonist.
BA5502 Imidafenacin

Summary: Imidafenacin (KRP-197; ONO-8025) is a potent and selective M3 receptor inhibitor.
BA5503 Darifenacin

Summary: Darifenacin (UK88525) is an M3 muscarinic-type receptor antagonist.
BA5504 PQCA

Summary: PQCA is a highly selective and potent modulator of muscarinic receptor-positive mutations.
BA5505 JHU37160

Summary: JHU37160 is a potent and permeable agonist across the blood-brain barrier.
BA5506 Aceclidine

Summary: Aceclidine (Quinuclidin-3-ylacetate) is a modulator and agonist of the M3 muscarinic acetylcholine receptor (EC:40 μM).