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Biochemical Reagent
Signaling pathways

Signaling pathways

BA7388 EN219

Summary: EN219 is a synthetic covalent ligand with moderate specificity acting on N-terminal cysteine C8.
BA7389 SENP1-IN-1

Summary: SENP1-IN-1 is an inhibitor of specific de-SUMOized proteases.
BA7390 EN450

Summary: EN450 is a targeted cysteine-responsive covalent molecular gel degrader.
BA7391 WS-383

Summary: WS-383 is a potent, selective and reversible interaction inhibitor.
BA7392 Cbl-b-IN-5

Summary: Cbl-b-IN-5 is an inhibitor (=3-10 μM).
BA7393 BC-1382

Summary: BC-1382 is a potent ubiquitin E3 ligase inhibitor that specifically disrupts the HECTD2/PIAS1 interaction (≈5 nM).
BA7395 UC-764864

Summary: UC-764864 is an inhibitor.
BA7396 Smurf1-IN-1

Summary: SMURF1-IN-1 is an orally active selective inhibitor of specific E3 ubiquitin protein ligase 1.
BA7397 Rugonersen

Summary: Rugonersen (RG6091; RO7248824) is a locked nucleic acid (LNA)-modified antisense oligonucleotides (ASOs) that reduces ubiquitin protein ligase E3A (UBE3A) silencing.
BA7398 BAY-85-8501

Summary: BAY-85-8501 is a potent, selective inhibitor of human neutral lipase.