Signaling pathways
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BA2642 MC-betaglucuronide-MMAE-1Summary: MC-betaglucuronide-MMAE-1 is part of. -
BA2643 DM21Summary: DM21 is a cleavable affix of an ADC active molecule and linker (ADClinker). -
BA2645 Mal-PEG4-VC-PAB-DMEA-PNU-159682Summary: Mal-PEG4-VC-PAB-DMEA-PNU-159682 is an active molecule-coupling consisting of the ADC connector Mal-PEG4-VC-PAB and the potent ADC cytotoxin DMEA-PNU-159682. -
BA2646 Amino-PEG4-Val-Cit-PAB-MMAESummary: Can be used to synthesize antibody-coupled reactive molecules (ADCs). -
BA2647 DBCO-PEG4-Val-Cit-PAB-MMAFSummary: DBCO-PEG4-Val-Cit-PAB-MMAF consists of degradable (cleavable) 4-unit PEG-containing (DBCO-PEG4-Val-Cit-PAB) and MMAF. -
BA2648 Mal-PEG8-Val-Cit-PAB-MMAESummary: Mal-PEG8-Val-Cit-PAB-MMAE is part of the antibody-coupled active molecule ADC. -
BA2649 DBCO-PEG4-VA-PBDSummary: DBCO-PEG4-VA-PBD is an antibody-coupled active molecule consisting of the antitumor antibiotic Pyrrolobenzodiazepine (PBD) linked to DBCO-PEG4-VA. -
BA2650 MAL-di-EG-Val-Cit-PAB-MMAESummary: It is composed of MonomethylE (MMAE), a highly potent microtubule inhibitor, coupled with the peptide linker MAL-di-EG-Val-Cit-PAB. -
BA2651 MC-SN38Summary: MC-SN38 is an active molecular coupler consisting of SN38, a potent microtubule disruptor, and a non-cleavable MClinker for the synthesis of antibody active molecular couplers (ADCs). -
BA2652 MMAE-SMCCSummary: MMAE-SMCC is an antibody-coupled active molecule consisting of MMAE, a potent inhibitor of mitotic and microtubule proteins, and SMCC, a connector.

