Signaling pathways
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BA3677 BOLD-100Summary: BOLD-100 (NKP-1339; IT-139) is a first-in-class ruthenium anticancer reagent developed for solid cancers with few side effects. - BA3678 IsodunnianolSummary: Isodunnianol is an autophagy inducer.
- BA3679 IsodeoxyelephantopinSummary: Isodeoxyelephantopin is a sesquiterpene lactone that can be isolated from Elephantopusscaber.
- BA3680 Desfluoro-ezetimibeSummary: Desfluoro-ezetimibe is a defluorinated impurity of Ezetimibe.
- BA3681 PHY34Summary: PHY34 an inhibitor of and consequent inhibition of autophagy with a nanomolar effect.
- BA3682 FAAH-IN-1Summary: FAAH-IN-1 is a fatty acid amide hydrolase inhibitor.
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BA3683 MLi-2Summary: MLi-2 is an orally active, highly selective inhibitor. - BA3684 XL01126Summary: XL01126 is a potent (14 nM (G2019SLRRK2) and 32 nM (WTLRRK2)) consisting of the VHL ligand VH101,thiol (HY-47851, blue portion) and inhibitor HG-10-102-01 (HY-13488, red portion).
- BA3685 PFE-360Summary: PFE-360 (PF-06685360) is a potent, selective, blood-brain barrier-crossing, orally effective inhibitor.
- BA3686 JH-II-127Summary: JH-II-127 an orally effective, highly potent, selective and brain-permeable inhibitor with values of 6, 2 and 48 nM for wild-type and and mutant, respectively.