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Biochemical Reagent
Signaling pathways

Signaling pathways

BA9081 MRT-14

Summary: MRT-14 is a potent antagonist.
BA9082 IHR-1

Summary: An antagonist.
BA9083 SRI-011381

Summary: An activator of a signaling pathway having oral biological activity.

≥9.9 mg/mL
BA9084 Luspatercept

Summary: Luspatercept (ACE-536) is a recombinantly modified ActRIIB fusion protein that binds to transforming growth factor beta superfamily ligands.
BA9085 SJ000063181

Summary: SJ000063181 is a potent signaling activator, ≤1μM.
BA9086 Trabedersen

Summary: Trabedersen (AP12009) is an antisense oligodeoxynucleotide that specifically inhibits (TGF-beta/Smad).
BA9087 Mongersen

Summary: Mongersen (GED-0301) is an antisense oligonucleotide with specific and oral activity.
BA9089 ALK5-IN-34

Summary: ALK5-IN-34 is a selective activin receptor-like kinase (ALK) inhibitor with oral activity.
BA9090 Adavivint

Summary: Adavivint (SM04690; Lorecivivint) is a potent, selective inhibitor of typical signaling pathways.
BA9091 KYA1797K

Summary: KYA1797K is a potent, selective inhibitor.