Signaling pathways
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BA7238 CLK8Summary: CLK8 is a potent and specific inhibitor that disrupts the interaction between CLOCK and BMAL1 and interferes with CLOCK nuclear translocation. -
BA7239 KL044Summary: KL044 is a stabilizer for the clock protein cryptochrome (CRY).
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BA7240 KS15Summary: KS15 is an inhibitor of the interaction between cryptochrome and heterodimers.
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BA7241 KL201Summary: KL201, a circadian modulator, is an isoform-selective cryptochrome 1 (CRY1) stabilizer.
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BA7242 Dafadine-ASummary: Dafadine-A is a dafadine analog.
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BA7243 BergamottinSummary: Bergamottin is a potent competitive inhibitor.
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BA7244 BergaptolSummary: Bergaptol is an inhibitor of enzyme debenzylation with an IC of 24.92 μM.
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BA7245 SoticlestatSummary: Soticlestat (TAK-935; OV935) is a first-in-class, potent, selective, orally active cholesterol 24-hydroxylase inhibitor.
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BA7246 MephenytoinSummary: An anticonvulsant that serves as a CYP2C19 and CYP2B6 substrate for epilepsy and CYP enzyme metabolism -
BA7248 FadrozoleSummary: A potent, selective, and nonsteroidal aromatase inhibitor