Signaling pathways
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BA4244 KIF18A-IN-2Summary: KIF18A-IN-2 was a potent inhibitor (=28nM). - BA4245 CCB02Summary: CCB02 is a selective interaction inhibitor.
- BA4246 KIF18A-IN-7Summary: KIF18A-IN-7 is an orally active inhibitor.
- BA4247 PironetinSummary: Pironetin is an alpha/beta unsaturated lactone isolated from Streptomyces species.
- BA4248 OmbrabulinSummary: Ombrabulin (AVE8062) is a derivative of CA-4 phosphate.
- BA4249 Flutax-2Summary: Flutax-2 is an active fluorescent derivative of Paclitaxel that binds to polymerized αβ-microtubulin dimers.
- BA4250 LP-261Summary: LP-261 is a potent antimitotic agent with oral activity.
- BA4251 7-Epi-docetaxelSummary: 7-Epi-10-oxo-docetaxel is an impurity of docetaxel (docetaxel).
- BA4252 AM-9022Summary: AM-9022 is an orally active, potent, and selective inhibitor.
- BA4253 TPI-287Summary: TPI-287 is a microtubule stabilizer that crosses the blood-brain barrier.