Signaling pathways
-
BA7245 SoticlestatSummary: Soticlestat (TAK-935; OV935) is a first-in-class, potent, selective, orally active cholesterol 24-hydroxylase inhibitor. - BA7246 MephenytoinSummary: Mephenytoin is an anticonvulsant.
- BA7247 DihydromethysticinSummary: Dihydromethysticin kavalactone.
- BA7248 FadrozoleSummary: Fadrozole (CGS16949A free base) is a potent, selective and non-steroidal inhibitor.
- BA7249 7-EthoxycoumarinSummary: 7-Ethoxycoumarin is a substrate for cytochrome P450 (CYP450).
- BA7250 CurcumenolSummary: Curcumenol is a highly effective inhibitor.
- BA7251 LKY-047Summary: LKY-047, a derivative of Decursin, is a potent and selective reversible competitive inhibitor of cytochrome P45022J2.
-
BA7252 OpevesostatSummary: A cholesterol side chain cleavage enzyme (CYP11A1) inhibitor. - BA7253 TiclopidineSummary: Ticlopidine (PCR5332) is an antithrombotic precursor.
- BA7254 N-Desmethyl-ApalutamideSummary: N-Desmethyl Apalutamide, the active metabolite of Apalutamide, is a low activity androgen receptor antagonist with one-third the activity of Apalutamide.