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In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
TG100801 is a multi-kinases inhibitor. It is a pro-drug version of TG100572. [1]
TG100572 inhibits several growth factor receptors in addition to Src family kinases. TG100801 significantly inhibited laser-induced CNV in mice, and suppressed fluorescein leakage from the vasculature and retinal thickening measured by optical coherence tomography in a rat model or retinal vein occlusion. TG100801 may play as a new topically applied treatment approach for ocular neovascularization and retinal edema. The highest concentration of TG100801 was found at the front of the rat eye (conjunctiva and cornea). [1]
Reference:1. Doukas J, Mahesh S, Umeda N et al. Topical administration of a multi-targeted kinase inhibitor suppresses choroidal neovascularization and retinal edema. J Cell Physiol. 2008 Jul;216(1):29-37.