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Arctigenin

Catalog No.
N2399
Anti-inflammatory, antiproliferative
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$50.00
In stock
20mg
$67.00
In stock

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Antioxidant, anti-inflammatory, antiproliferative and antiviral agent. Inhibits LPS-induced iNOS expression via inhibition of IκBα phosphorylation and p65 nuclear translocation (IC50 = 10 nM). Inhibits HIV-1 replication in vitro. Also potently inhibits MKK1 (MEK1) (IC50 = 0.5 nM) and provides neuroprotection by binding to kainate receptors.

Chemical Properties

Physical AppearanceA solid
StorageDesiccate at -20°C
M.Wt372.41
Cas No.7770-78-7
FormulaC21H24O6
Synonyms(-)-Arctigenin
Solubility≥17.2mg/mL in DMSO
Chemical Name(3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
SDFDownload SDF
Canonical SMILESCOC1=C(C=C(C=C1)CC2COC(=O)C2CC3=CC(=C(C=C3)O)OC)OC
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

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