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IDO inhibitor 1

IDO inhibitor 1

Catalog No.

A3483

Indoleamine-2,3-dioxygenase inhibitor

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Grouped product items
Size	Price	Stock
5mg	$233.00	In stock
10mg	$355.00	In stock
25mg	$514.00	In stock
50mg	$841.00	Ship with 10-15 days

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Background
Chemical Properties
Quality Control

Background

IDO inhibitor 1 is a potent and novel indoleamine-2,3 dioxygenase (IDO) inhibitor with IC50 value <100 nM.

IDO is an enzyme that catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine and permits tumor cells to escape the immune system.

Reference:
[1]. Andrew P. Combs, et al. 1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase. Patent Numeber: EP 2315756 A2
http://www. google.com/patents/EP2315756A2?cl=en

Chemical Properties

Physical Appearance	A solid
Storage	Store at -20°C
M.Wt	438.23
Cas No.	1204669-37-3
Formula	C₁₁H₁₃BrFN₇O₄S
Solubility	insoluble in H2O; ≥19.35 mg/mL in DMSO; ≥34.75 mg/mL in EtOH with ultrasonic
Chemical Name	(E)-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-((2-(sulfamoylamino)ethyl)amino)-1,2,5-oxadiazole-3-carboximidamide
SDF	Download SDF
Canonical SMILES	BrC1=CC(/N=C(NO)\C2=NON=C2NCCNS(=O)(N)=O)=CC=C1F
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

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Purity = 99.83%

Chemical structure

IDO inhibitor 1

mRNA synthesis

Tyramide Signal Amplification (TSA)

Phos Binding Reagent Acrylamide

Cell Counting Kit-8 (CCK-8)

Inhibitor Cocktails

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Chemical Properties

Quality Control

Quality Control & MSDS

Chemical structure

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