Search results for: 'research-area gpcr-g-protein'
- Tenovin-1Catalog No. :A4203SIRT2 inhibitor, activates p53Tenovin-1, a small molecule discovered by a cell-based screen, is a bio-active activator of p53 that elevates the levels of p53 protein, p53-downstream target p21CIP/WAF1 protein and mRNA and protects p53 from mdm2-mediated degradation with little impact on p53 synthesis.
- Tenovin-6Catalog No. :A8302SIRT inhibitor and p53 activatorTenovin-6 is an analog of tenovin-1 with more water-soluble and it inhibits the protein deacetylase activities of SIRT1, SIRT2 and SIRT3 with IC50 value of 21 μM, 10 μM, and 67 μM, respectively .