Search results for: 'research-area stem-cell hippo-signaling'
- LDN-193189Catalog No. :A8324ALK inhibitor,potent and selectiveLDN193189 is a selective transcriptional activity morphogenetic protein (BMP) type I receptors inhibitor. It inhibits activin receptor-like kinase-2 (ALK2) and ALK3 with IC50 values of 5 nM and 30 nM, respectively .
- DMH-1Catalog No. :B3686Selective BMP ALK2 receptorDMH1 is a small molecule inhibitor of bone morphogenetic protein (BMP) signaling with IC50 value of 107.9nM against ALK2 .
- 2,3-DCPE hydrochlorideCatalog No. :A4447Bcl-XL protein expression downregulatorSelectively induces apoptosis and downregulates Bcl-XL protein expression in various human cancer cells versus normal cells in vitro. IC50 values are 0.89 and 12.6 μM for LoVo human colon cancer cell line and normal human fibroblasts respectively. Induces p21 expression and S-phase arrest in cancer cells via ERK-mediated pathways.