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LY450108AMPA receptor potentiator

LY450108

Catalog No. A3578
Size Price Stock
5mg $246.00 Please Inquire
10mg $339.00 Please Inquire
50mg $986.00 Please Inquire
200mg $2,262.00 Please Inquire

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Sample solution is provided at 25 µL, 10mM.

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Chemical structure

LY450108

LY450108 Dilution Calculator

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Chemical Properties

Cas No. 376594-67-1 SDF Download SDF
Synonyms LY 450108;LY-450108
Chemical Name 3,5-difluoro-N-(4-(1-(1-methylethylsulfonamido)propan-2-yl)phenyl)benzamide
Canonical SMILES CC(S(=O)(NCC(C1=CC=C(NC(C2=CC(F)=CC(F)=C2)=O)C=C1)C)=O)C
Formula C19H22F2N2O3S M.Wt 396.45
Solubility DMSO Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

Background

LY450108 is an alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor potentiator. AMPA receptors mediate most of the excitatory neurotransmission and play a key role in synaptic plasticity in the mammalian central nervous system (CNS). Recent evidence has shown that in addition to modulating fast synaptic plasticity and memory processes, AMPA receptor potentiators alter downstream signalling pathways and may thereby have utility in other CNS disorders.